Downstream processing (also known as DSP) refers to the recovery and purification of a drug substance (DS) from natural sources, such as animal or bacterial cells. It is defined as the unit operations that follow cell growth and expansion; with a purpose to isolate, purify, and concentrate the previously synthesized drug substance or other product from the complex bulk matrix. In this course, students will learn separation techniques with hands-on experience using a small-scale Akta Prime chromatography system to perform both Anion Exchange and Hydrophobic Interaction Chromatography.
- Bioprocess Technicians
- Bioprocess Engineers
- Manufacturing Associates
- Purification Technicians
- Purification Lab Analysts
- Chromatography Associates
Day 1
- Introduction
- Lab: AktaPrime Chromatography ID
- Process Operation of GFP
- GFP Chromatography Run
Day 2
- Introduction
- Lab: Process Operation of GFP
- GFP Chromatography Run
- Learn about Anion Exchange chromatography.
- Learn about Hydrophobic Interaction chromatography.
- Perform hands-on techniques in small scale chromatography.
Delivered in-person in a classroom or lab setting.
Downstream processing (also known as DSP) refers to the recovery and purification of a drug substance (DS) from natural sources, such as animal or bacterial cells. It is defined as the unit operations that follow cell growth and expansion; with a purpose to isolate, purify, and concentrate the previously synthesized drug substance or other product from the complex bulk matrix. In this course, students will learn separation techniques with hands-on experience using a small-scale Akta Prime chromatography system to perform both Anion Exchange and Hydrophobic Interaction Chromatography.
- Bioprocess Technicians
- Bioprocess Engineers
- Manufacturing Associates
- Purification Technicians
- Purification Lab Analysts
- Chromatography Associates
Day 1
- Introduction
- Lab: AktaPrime Chromatography ID
- Process Operation of GFP
- GFP Chromatography Run
Day 2
- Introduction
- Lab: Process Operation of GFP
- GFP Chromatography Run
- Learn about Anion Exchange chromatography.
- Learn about Hydrophobic Interaction chromatography.
- Perform hands-on techniques in small scale chromatography.