Freeze-Drying Fundamentals

Freeze-Drying Fundamentals
850 Oval Drive
Raleigh, NC 27695

Description

Learn the principles and techniques of manufacturing lyophilized biopharmaceutical products. Biologics, vaccines, and other pharmaceutical ingredients may require freeze-drying and moisture analysis for product stabilization and long-term storage. This course gives you a theoretical foundation and practical experience in lyophilization.

Topics Include

The course is 20 hours, conducted in two 8-hour sessions and one 4-hour session on the third day and covers:

  • Principles of lyophilization: primary drying, secondary drying, eutectic points, and collapse temperatures
  • Lyophilization cycle set up and operation
  • Thermal analysis of product formulations using Differential Scanning Calorimetry (DSC) and Freeze-Drying Microscopy
  • Residual moisture content analysis of finished product
  • Troubleshooting lyophilization failures

Learning Objectives

  • Discuss the principles and theory underlying lyophilization
  • Perform freeze-dryer cycle development
  • Relate product formulations to freeze-drying success
  • Troubleshoot freeze-dried product failures

Audience

Technicians in pharmaceutical manufacturing including:

  • Lyophilization specialists
  • Validation Engineers
  • Process Technicians
  • Production Technicians
  • Quality Control/Quality Assurance personnel
Instructor(s)
Rebel Umphlett
Class Dates
  • October 23, 2018
  • October 24, 2018
  • October 25, 2018
Class Days & Times
  • Tue - 8:00 AM to 5:00 PM
  • Wed - 8:00 AM to 5:00 PM
  • Thu - 8:00 AM to 12:00 PM
Class Level
Intermediate
Lecture Hours
10.00
Lab Hours
10.00
Total Contact Hours
20.00
Building
BTEC
Room
250B
Format
Face-to-Face
Course ID
199258